The ralated 10 pathways were Pathways in cancer, Hepatitis B, MAPK signaling pathway, Chemical carcinogenesis-receptor activation, AGE-RAGE signaling pathway in diabetic complications, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Transcriptional misregulation in cancer, HIF-1 signaling pathway, Platinum drug resistance, EGFR tyrosine kinase inhibitor resistance (Fig. 2E-F). This evidence concerns the gene HIF1A and atherosclerosis.