The alkali-soluble polysaccharides contained in Angelica have the activity of stimulating the proliferation of immune cells (splenocytes, abdominal macrophages and natural killer cells), as well as promoting the release of cytokines (TNF-α, IL-2) and gamma interferon (IFN-γ) to promote apoptosis of tumor cells. The gene discussed is TNF; the disease is neoplasm.