A polyfunctional T response intervened in this regulation, where both pro-inflammatory (tnf-α, il12, il-6, il-17, ifn-γ) and anti-inflammatory (il-10, tgf-β) cytokines that characterize Th1, Th17 and Treg activation profiles were detected in HF-stimulated BMDCs primed splenocytes compared with untreated cells. The gene discussed is IFNG; the disease is hydrops fetalis.