In the other hand, during the infection course, tissue inflammation characterized by a pro-inflammatory Th17 profile with an expression of RORγt, IL-17, IL-10 and IL-6 significantly increased in the middle stage (day 30-90) in a mouse model of Echinococcus infection (Ma et al., 2014; Pang et al., 2014). Here, IL10 is linked to infection.