In addition, plasma endostatin [76], brain natriuretic peptide (BNP) [77,78], serum ferritin [79,80], plasma fibroblast growth factor [81], plasma trimethylamine-N-oxide content [82], hypersensitive cardiac troponin [83], coagulant-related factors C-type lectin receptor 2 and anti-phosphatidylserine [84,85], circulating IGF-1 [86], plasma lipid metabolism [87-89], plasma D-dimer [90] and other biochemical metabolites may be related to the prognosis of AIS. This evidence concerns the gene NPPB and androgen insensitivity syndrome.