FMRP is an RNA-binding protein that regulates synaptic function through regulation of protein translation (Maurin et al., 2018), and its deficiency results in the characteristic FXS phenotypes including developmental disability, anxiety, interfering repetitive behavior, language delay, and abnormal sensory processing (Enifeld & Hall, 1992; Kaufmann, 2002; Kaufmann et al., 1999; Loesch et al., 1993; Loesch et al., 2003; Rogers et al., 2001; Smith et al., 2016). Here, FMR1 is linked to fragile X syndrome.