CD4+ TILs subset was more enriched in meningiomas (log median 6.37, IQR [5.62, 7.25]) than in glial tumours (p < 0.001), whereas the expression in gliomas was significantly higher in GBMs (log median 5.62, IQR [4.67, 6.30]) than in astrocytomas (log median 4.50, IQR [2.50, 5.60]) (p = 0.0026). This evidence concerns the gene CD4 and astrocytoma (excluding glioblastoma).