Within the cancer groups, there was an up-regulation of two species of critical Cers, designated Cer (d18:1_16:0) and Cer (d18:1_18:0), but a down-regulation was observed in 55 types of SLs, including 40 species of SMs (d18:1_16:0), SM (d18:1_18:1), and SM (d18:1_24:0). Here, CBLN1 is linked to cancer.