We were the first to describe a role for EDI3 in cancer, showing that high EDI3 expression is associated with metastasis and worse survival in human endometrial and ovarian cancer [11], and our earlier studies in multiple cell lines of different cancer types revealed that EDI3 is important in cell migration, adhesion, and spreading [11, 26, 27]. The gene discussed is GPCPD1; the disease is cancer.