Previous studies have examined the potential mechanisms by which thyroid hormones affect PCOS, mainly through the following: (1) Although currently an accepted genotypic milieu has not been set up, gene polymorphisms such as FBN3 gene variants cause the pathogenesis of PCOS and HT by affecting TGFb’s activity [32, 33]. This evidence concerns the gene TGFB1 and polycystic ovary syndrome.