Although the circulating levels of TC, FFAs, and HDL showed no differences between Pai mice and their wt littermates, the levels of plasma TGs were significantly elevated in Pai/Pai mice compared to wt or Pai/wt mice (p < 0.05, Fig. 6), indicating t10c12-CLA-induced hypertriglyceridemia in Pai/Pai mice. The gene discussed is SELPLG; the disease is hypertriglyceridemia.