FTH1 and myocardial ischemia: The myocardial ischemia-reperfusion procedure upregulated embryonic lethal anomalous visual-like protein 1 and cellular iron levels, increased lactate dehydrogenase activity, but significantly decreased GPX4 activity and FTH1 and GSH levels, suggesting that ferroptosis occurs during myocardial ischemia-reperfusion [141].