The ability of NDRG1 to inhibit the EMT occurs through (1) maintaining the cell membrane localization of E-cadherin and β-catenin that forms part of the adherens junction complex; (2) inhibiting the expression of the EMT marker, vimentin; and (3) blocking cell migration and invasion of prostate and colon cancer cells (7). The gene discussed is NDRG1; the disease is malignant colon neoplasm.