PPARGC1A and steatosis: This is consistent with the already known role of p63 in the mitochondrial function in the hepatocytes, in which TAp63 controls the mitochondrial fatty acid oxidation via PGC1α, CPT1a and different OXPHOS complex subunits under steatosis, and suggests a tight control of mitochondrial function by TAp63 across the whole spectrum of steatohepatitis [22].