Recently, Zhu and co-workers [48] screened 1481 Chinese high-risk BC patients for 16 FA genes and reported 38 pathogenic mutation carriers in the 12 unconfirmed BC genes after excluding BRCA1, BRCA2, PALB2, and RAD51C. Of these genes, FANCA was the most commonly mutated (0.54%) followed by FANCD2 (0.41%). The gene discussed is FANCD2; the disease is breast cancer.