TG and thyroid gland carcinoma: The results of a clinical trial (NCT02862470) in patients with recurrent thyroid cancer showed that although serum thyroglobulin was not detected in 3 patients with thyroid cancer, the levels of urinary exosomal thyroglobulin were consistently increased, indicating that urinary exosomal thyroglobulin protein is a potential marker for predicting thyroid cancer recurrence [82].