TRAF7 and mesothelioma: The WD40 domain of TRAF7 has recently emerged as a common mutational hot spot for a subset of unusual human tumors, including mesotheliomas (44, 45), adenomatoid tumors of the genital tract (46), fibromyxoid spindle-cell sarcomas of soft tissue (47), perineurioma nerve sheath tumors (48), and meningiomas (49, –, 51).