RACK1 has been frequently described to promote viral infection via various mechanisms, including immune escape [51,52] , viral release[53], enhancement of viral replication[54] , cellular translation machinery[55], intracellular docking sites for viral proteins[56] , IRES-dependent viral translation [57,58] , formation of viral replication organelles[50], induction of ribosome-based stress signaling[59], and inhibition of virus-induced apoptosis[60]. The gene discussed is RACK1; the disease is viral infectious disease.