Other symptoms of diabetes mellitus, such as intestinal barrier dysfunction, can also be alleviated by I. obliquus treatment through upregulation of Ki-67, zonula occludens-1 (ZO-1), and mucin-2 (MUC2) expression (Su et al. 2022), showing the promising role of I. obliquus for the relief of diabetes and its consequent complications. This evidence concerns the gene MKI67 and diabetes mellitus.