The AG genotype of the PYCARD A/G (rs372507365) polymorphism revealed a statistically significant association with periodontal disease and atherosclerotic CHD with periodontitis susceptibility (OR = 7.12; 95% CI, 0.0066-0.5678) and (OR = 5.83; 95% CI, 0.004540-0.3461) in this study population as compared to the AA genotype (Table 3). The gene discussed is PYCARD; the disease is periodontitis.