Other antibodies were largely unremarkable (DS-DNA antibody, anti-RNP, anti-Smith, Scleroderma antibody, SSA/SSB antibody, Jo-1 antibody, RF, pANCA, cANCA, anti-LKM, anti-Smooth muscle, anti-mitochondrial) leading to a likely diagnosis of systemic lupus erythematosus (SLE) flare. Here, RNPC3 is linked to systemic lupus erythematosus.