CXI: cachexia index; mGPS: modified Glasgow Prognostic Index; BMI: body mass index; Adj: adjuvant; CHT: chemotherapy; RT: radiotherapy; ER: estrogen receptor; HER-2: human epidermal growth receptor-2, HR: hazard ratio; OS: overall survival; DFS: disease-free survival. This evidence concerns the gene ESR1 and Cachexia.