TNF and lung cancer: ROC curve analysis showed that IFN-γ, IP-10, MIP-1α, MIP-1β, MIP-2, and TNF-α had a significantly predictive efficiency in the diagnosis of lung cancer, and the AUC values of the above biomarkers were 0.800, 0.656, 0.905, 0.921, 0.914, and 0.824 (Table 3 and Fig. 1).