KEGG analysis identified that the upregulated DEGs were primarily enriched in the following pathways: staphylococcus aureus infection, complement and coagulation cascades, cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, neuroactive ligand-receptor interaction, etc., while the downregulated DEGs were enriched in calcium signaling pathway, MAPK signaling pathway, axon guidance, neurotrophin signaling pathway, etc (Fig. 3B). Here, BDNF is linked to staphylococcus aureus infection.