ADIPOQ and eosinophilia-myalgia syndrome: Increased oxidative stress, mitochondrial dysfunction, and other abnormalities in energy metabolism in EMs increase the survival of ectopic endometrial cells; therefore, adiponectin may regulate energy metabolism in Endometrial cells in the microenvironment of the ectopic lesions to affect the ability of Endometrial cells to proliferate, migrate, and invade ectopic sites, and thus play a role in the pathogenesis of EMs; however, the specific mechanism requires further research.