The presence of both AdipoR1 and AdipoR2 has been confirmed in uterine leiomyoma cells, and adiponectin exerts a significant inhibitory effect on the proliferation of uterine Eker leiomyoma tumor 3(ELT-3) cells in rats (Wakabayashi et al., 2011; Strzałkowska et al., 2021). This evidence concerns the gene ADIPOQ and uterine corpus leiomyoma.