In vitro cell experiments, Adiponectin has been shown to inhibit the proliferation of ectopic endometrial cells in a dose- and time-dependent manner while simultaneously increasing the expression of both AdipoR1 and AdipoR2 to inhibit EMs development; these findings suggest that adiponectin may serve as a beneficial factor that limits the pathogenesis of EMs (Bohlouli et al., 2016). The gene discussed is ADIPOR2; the disease is eosinophilia-myalgia syndrome.