Current research on the pathogenesis of EMs and the function of adiponectin have shown that adiponectin may play a special regulatory role in multiple biological processes related to the pathogenesis of EMs, such as apoptosis, autophagy, inflammatory response, angiogenesis, fibrogenesis, energy metabolism, and estrogen regulation. The gene discussed is ADIPOQ; the disease is eosinophilia-myalgia syndrome.