Adiponectin enhances CXCL1 secretion, which, in turn, promotes VEGF secretion and angiogenesis (Kiefer and Siekmann, 2011) in various cancers, including colon (Cai et al., 2016) and ovarian cancer (Ouh et al., 2019). Here, CXCL1 is linked to ovarian carcinoma.