Additionally, the higher prevalence of the PER2 VNTR 4R/3R and 3R/3R genotypes in pancreatic cancer patients compared to healthy controls suggested that a greater proportion of the 3R allele in the PER2 VNTR may be a risk factor for pancreatic cancer (Dagmura et al., 2021). This evidence concerns the gene PER2 and pancreatic neoplasm.