CCNB1 and hepatocellular carcinoma: In addition, the content of CCNB1 in the HCC cells was decreased by transfection with si-CCNB1 (Figure 6b; p < 0.001), while miR-622 upregulation markedly reduced the migration (Figures 6c–6f; p < 0.001) and invasion (Figures 6g and 6h; p < 0.001) of the HCC cells.