Parameters affecting 28-day mortality; the presence of primary SRD flare-up, renal involvement before hospitalization, neurological involvement before hospitalization, ARF, the presence of AKI, presence of sepsis, presence of septic shock, presence of cardiogenic shock, pneumonia, need for IMV, and platelet, BUN, creatinine, ALT, PLR values were included in the logistic regression analysis. This evidence concerns the gene GPT and Sepsis.