When considering the results of a series of multivariable linear regressions, adjusted for some covariates such as sex, DBP, and CRP, plasma levels of many lysoPCs and PCs, together with those of some acylcarnitines and one SM, were shown to be associated with PWS (vs. non-PWS, i.e., EOB), with a FC ranging from 1.83 to 4.47, indicating higher levels of all metabolites in PWS than EOB group. The gene discussed is CRP; the disease is Prader-Willi syndrome.