On the contrary, to discriminate astrocytoma, much fewer features were found to be relevant, including only 2 genes DRG2 and THRAP3, both already reported in glioma studies, and the methylation sites cg24899806 (KCND2), cg19093820 (GPR156), cg26077062 (SYBU), cg04951819 (CCDC77) and cg03780927 (BCL9 L), where GPR156 and CCDC77 were never reported in glioma, and the latter also never reported in any other cancer studies. The gene discussed is DRG2; the disease is central nervous system cancer.