KCND2 and astrocytoma (excluding glioblastoma): Although its function in glioma is still not completely elucidated, it was recently demonstrated to be positively correlated with several steps in anti-tumor immune response,53 and its depletion was shown to promote survival.54 In the case of KCND2, it showed a lower level of methylation and a higher expression level in astrocytoma.