Although all these genes were revealed to be relevant in biological processes underlying GBM and especially in its highly proliferative and invasive profile, the survival analysis showed that only the expression of the genes CCDC46 (with updated symbol CEP112), CD58, EFEMP2, and KIAA1614 were significant in patient survival probability, the first 2 in LGG and the last 2 in GBM types. This evidence concerns the gene CD58 and glioblastoma.