A logistic regression model was performed to determine the effects of clinical (age, sex, weight SDS, length SDS, and weight-for-length SDS), and hormonal (serum FSH, LH, estradiol, testosterone, prolactin, DHEA-S, TSH, FT4, IGF-1, IGFBP3, SHBG, AMH) markers on the cases with AD. The gene discussed is PLOD1; the disease is Alzheimer disease.