ELANE and metabolic dysfunction-associated steatohepatitis: In line with these reports, our data on the immunohistochemistry of NE and PR3 consistently demonstrate that neutrophilic CLSs form exclusively at sites of steatotic hepatocytes in liver specimens with MASH or borderline MASH, whereas the formation of neutrophilic CLSs was rare or absent in liver specimens with MASLD or normal liver histology.