A cutoff value for neutrophilic CLSs of 0.3 and 1.3 per 20× microscopic field demonstrated reasonable diagnostic accuracy to discriminate non-MASH and definite MASH, respectively (NE+ CLSs shown in Fig. 3; PR3+ CLS shown in Fig. S2). Here, PRTN3 is linked to metabolic dysfunction-associated steatohepatitis.