GSEA enrichment analysis of C02-CD5L-Macro indicated activation of pro-inflammatory and pro-fibrotic signaling pathways, pathways related to regulatory cell death (such as regulated necrosis and ferroptosis), lipid metabolism pathways, and pathways associated with sulfur metabolism (such as sulfate formation due to sulfide oxidation) in NAFLD patients compared to the controls. The gene discussed is CD5L; the disease is metabolic dysfunction-associated steatotic liver disease.