The PD-L1 TC/IC ≥ 1% subgroup was enriched for the SCLC-I subtype (14% vs. 2% in the PD-L1 TC/IC < 1% subgroup), whereas the combined prevalence of the neuroendocrine subtypes SCLC-A and SCLC-N was lower in the PD-L1 TC/IC ≥ 1% subgroup versus the PD-L1 TC/IC < 1% subgroup (81% vs. 92%) (Fig. 3B). This evidence concerns the gene CD274 and small cell lung carcinoma.