In breast cancer, Zhang et al. [19] found that BHLHE41 inhibited tumor invasion by inactivating the MAPK/JNK signaling pathway, which was accompanied by downregulation of SNAI1, SNAI2, VIM, and CDH2 and overexpression of CLDN1, CLDN4, and CDH1. This evidence concerns the gene BHLHE41 and neoplasm.