HMGA2 and infection: The transcriptome analysis revealed that among the TNF-α-induced Hmga2-WT-target genes identified by ChIP-seq (Fig. 6C), Hmga2-WT and Hmga2-5A both mildly activated the transcription of genes involved in infection and ribosome pathways to lesser degrees than the empty control in HSCs after the treatment with TNF-α, forming cluster 5 (Fig. 6G; Dataset EV8).