SLC19A1 and melanoma: Reanalyzing Perturb Cellular Indexing of Transcriptomes and Epitopes (Perturb-CITE) sequencing data from melanoma cells37, we found evidence for similar occasional loss of the entire chromosome 21 arising from editing of SLC19A1, located on the q arm (21q22.3) (Fig. 2e and Supplementary Table 2).