Similarly, the expression of genes related to antigen processing and presentation such as Tap1, Tap2, B2m, and Psmb9, was also upregulated in tumors from hsBCL9z96-treated CT26 tumor-bearing mice and MC38 tumor-bearing Bcl9/Bcl9l deficiency mice (Fig. 1f, g). Here, BCL9 is linked to neoplasm.