We verified that overexpression of AKT1 by infection with the constitutively active (CA)-AKT1 adenovirus containing an src myristoylation sequence and a GFP-tag, completely inhibited TG- and TU-induced c-Cas-3 expression in both WT and GRP94 KD cells (Fig. 3E, F). The gene discussed is AKT1; the disease is infection.