Pediatric cases of medically refractory focal epilepsy are often associated with cortical dysplasia, which can be modeled in mice using in‐utero electroporation to constitutively activate mTOR in cortical pyramidal neurons in a focal cortical region.[45] Evaluating our procedure in these models would require localization and mapping of the seizure focus or foci, which varies in location, size, and shape in these genetic models, and then planning and executing a mouse‐specific laser cut geometry. Here, MTOR is linked to cerebral cortical dysplasia.