Mutations in exons 8 and 9 of WT1 usually lead to abnormal zinc finger structures that disrupt DNA‐binding activity, which may cause a variety of inherited kidney diseases, including nephrotic syndrome, Wilms tumor, DDS syndrome, and so on.[14, 15] Upon differentiation, the WT1‐KO kidney organoids exhibited no nephron‐like structures and consisted almost exclusively of stromal cells (Figure S7a,b, Supporting Information). This evidence concerns the gene WT1 and Nephroblastoma.