Notably, EMP3, RGS16, PLAU, TAGLN2, STEAP3, CDHR1, OSMR, SERPINH1, PDPN, CHI3L1, ABCC3, SERPINE1, SOCS1, GPX8, GPNMB, CLEC5A, FOSL2, ICAM1, PRF1 and ITPRIP serve as prognostic markers for gliomas.9, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52. This evidence concerns the gene PLAU and central nervous system cancer.