Notably, EMP3, RGS16, PLAU, TAGLN2, STEAP3, CDHR1, OSMR, SERPINH1, PDPN, CHI3L1, ABCC3, SERPINE1, SOCS1, GPX8, GPNMB, CLEC5A, FOSL2, ICAM1, PRF1 and ITPRIP serve as prognostic markers for gliomas.9, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52. The gene discussed is GPX8; the disease is central nervous system cancer.