TNFRSF4 and neuroblastoma: To assess whether TNFRSF4 expression was functionally relevant important for the oncogenic capacities of neuroblastoma cells, we carried out siRNA-mediated knockdown of TNFRSF4 in Kelly (MYCN amplified) and SK-N-AS (non-MYCN amplified) neuroblastoma cells grown in vitro (Fig 7D).