Overall, 8 genes were identified as differentially expressed genes (DEGs) between GC tumor and nontumor tissues (eTable 9 in Supplement 1), with upregulated CDH3 and BAIAP2L2 and downregulated TMED6 also observed in advanced vs mild gastric lesions (eTable 11 in Supplement 1). Here, CDH3 is linked to gastric cancer.