They also showed the OATP3A1 as a bile acid efflux transporter.58 On the other hand, OATP3A1 has been shown toact as an uptake transporter for estrone-3-sulfate, prostaglandins,thyroxine, and vasopressin57−59 Hydrophilic bile acid ursodeoxycholicacid (UDCA) and its conjugate tauroursodeoxycholic acid (TUDCA) haveshown neuroprotective properties in a range of in vivo retinal diseases models60,61 and alleviation incataract formation in induced rat models.62,63 The role of OATP3A1 in bile acid homeostasis in the eye and in thepathogenesis of ocular disease requires further investigations. The gene discussed is SLCO3A1; the disease is Abnormal retinal morphology.