found CXCL13+CD8+T cells were a highly exhausted subtype of intratumoral CD8+T cells with impaired immune function and exhausted markers, and high infiltration of CXCL13+CD8+T cells in ccRCC could also demonstrate the immunoevasive contexture with an impaired CD8+T‐cell immunity, more pro‐tumor cells and fewer anti‐tumor factors.66 The gene discussed is CD8A; the disease is neoplasm.