CEBPA and leukemia: Sun et al[11] also demonstrated that the overexpression of the transcription factor HOXA9 in myeloid and B progenitor cells induced the emergence of leukemia-specific enhancers and reprogramed the enhancer landscape by recruiting the transcription factor CCAAT enhancer binding protein alpha (CEBPa) and the myeloid/lymphoid or mixed lineage leukemia 3 (MLL3)/MLL4 complex, leading to the activation of an ectopic embryonic gene program and promoting leukemogenesis.