HNRNPA1 and posterior cortical atrophy: In conclusion, we found that the variant of rs11973492 obstructed the generation ofcircHIBADH, which may act as a protein sponge and inhibitor of HNRNPA1 and other RBPs, consequently enhancing RNA splicing processes and subsequent MYC targeting, DNA repair, and E2F target signaling pathways, to play an oncogenic role in PCa.