In particular, in a large real-life European multicenter idiopathic pulmonary fibrosis (IPF) study, van der Vis JJ et al. showed that MUC5B minor allele carriers were significantly older at diagnosis (p = 0.001), and among patients ≥56 years of age at diagnosis, the 3-year cumulative incidence of death was lower among MUC5B minor allele carriers (39%) than among non-carriers (57%) (van der Vis et al., 2023). The gene discussed is MUC5B; the disease is pulmonary fibrosis.