TANGO2 and hypothyroidism: He was referred for genetic testing to rule out genetic epilepsy; an epilepsy panel from Invitae (San Francisco, CA, USA) was performed in December 2022, and studies revealed two pathogenic variants (deletion, exons 3–9, homozygous; c.57-?_*2502+?Del) in TANGO2, a gene associated with metabolic encephalopathy, rhabdomyolysis, hypothyroidism, and prolonged QT intervals and arrhythmias during metabolic crises, explaining his initial symptomatology and presentation.1