Multivariate logistic regression models(Model3) adjusting for potential confounders such as sex, age, race, education level, PIR, BMI, smoking status, drinking status, hyperlipidemia, hypertension, diabetes, physical activities status, ALT, AST, and lipid-lowering drugs, showed that the ORs for participants in Q2, Q3, and Q4 compared to those in Q1 based on their AIP were 2.00 (95% CI 1.03 to 3.91), 2.63 (95% CI 1.39 to 4.96), and 3.85 (95% CI 1.55 to 9.52), respectively (P for trend = 0.006). The gene discussed is GPT; the disease is hyperlipidemia.