CD274 and neoplasm: The detection rate of PD‐L1 expression was higher in CTC than in tumor tissues (53.0 versus 42.1%). There was no correlation between the two. Patients with PD‐L1 expression on tissue or CTCs had a median progression‐free survival (mPFS) of 5.6 months (n = 36, 95% confidence interval [CI] 3.6–7.5 months), significantly longer than those without PD‐L1 detection (n = 9, mPFS of 1.4 months, 95% CI 1.3–1.5 months, log‐rank p = 0.032).